方怀防,黄庆竹,张林碧,杨 敏,魏 蒙.ICP-MS法测定不同产地厚朴中金属元素[J].中南民族大学学报自然科学版,2018,(1):11-14
ICP-MS法测定不同产地厚朴中金属元素
Determination of Metal Elements in Magnolia officinalis from Different Habitats by ICP-MS
  
DOI:
中文关键词: 厚朴  金属元素  ICP-MS  不同产地
英文关键词: Magnolia officinalis  metal element  ICP-MS  different origins
基金项目:国家自然科学基金资助项目(21275165);中南民族大学人才引进资助项目(YCZY12020)
作者单位
方怀防1,黄庆竹1,张林碧2,杨 敏2,魏 蒙2 1 中南民族大学 化学与材料科学学院武汉 4300742 湖北中医药大学 药学院武汉 430065 
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中文摘要:
      为建立同时测定厚朴药材中多种金属元素含量的方法,并对其进行比较分析,经硝酸-高氯酸消解样品后,采用电感耦合等离子体质谱法(ICP-MS)测定了其中Mn,Fe,Ni,Cu,Zn等10种金属元素含量.结果表明:各元素标准曲线线性关系良好(r=0.9998~1.0000),加标回收率在90.57%~114.56%;不同产地厚朴样品中金属元素含量有明显差异,部分药材重金属含量超标.该方法简单、准确、检出限低,适合对药材样品金属含量的分析测定,结果可对厚朴的药理研究及质量控制提供参考.
英文摘要:
      In order to establish a method for simultaneous determination and perform a comparative analysis of the various metal elements in Magnolia officinalis from different habitats, the contents of Mn, Fe, Ni, Cu, Zn and ten other metal elements were determined by inductively coupled plasma mass spectrometry (ICP-MS) after the samples were digested by nitric acid and perchloric acid. Good linear relationship of standard curves for each element was obtained (r=0.9998—1.0000), with standard recovery rates ranging from 90.55% to 114.4%. Significant variation of metal contents of Magnolia officinalis from different regions was observed, and heavy metals in some samples exceeded the limit set by national standards. The method is simple, sensitive, and of low detection limit .It is suitable for the analysis and determination of metal elements in medicinal materials, and the results may serve as a reference for pharmacological study and quality control of Magnolia officinalis.
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