覃 瑞,兰德庆, 黄 文,刘 虹.金腰属植物的化学成分和药理活性研究进展[J].中南民族大学学报自然科学版,2018,(2):54-59
金腰属植物的化学成分和药理活性研究进展
Research Progress on Chemical Constituents and Pharmacological Activities of Chrysosplenium spp.( Saxifragaceae)
  
DOI:10.12130/znmdzk.20180112
中文关键词: 金腰属  化学成分  药理活性  研究进展
英文关键词: Chrysosplenium  chemical constituents  pharmacological activities  research progress
基金项目:国家科技基础性工作专项重点项目资助( 2014FY110100);湖北省科技条件平台建设专项(2017BEC014)
作者单位
覃 瑞,兰德庆, 黄 文,刘 虹* 中南民族大学 武陵山区特色资源植物种质保护与利用湖北重点实验室湖北 武汉 430074 
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中文摘要:
      介绍了虎耳草科金腰属植物多为传统中草药. 该属植物裸茎金腰特有成分多种三甲氧基黄酮对人红白血病细胞株K562 具有显著抑制作用,该属其他物种的药理活性也有陆续报道, 因此该属植物的化学成分和药理活性值得深入研究.通过对金腰属植物中黄酮、 挥发油以及萜类化学成分及生物活性研究进行归纳和总结, 以期为系统提示金腰属植物的活性物质等提供参考.
英文摘要:
      Plants of Chrysosplenium ( Saxifragaceae) were usually reported as traditional Chinese herbal medicines. The active ingredients such as trimethoxyflavones separated from C.nudicaule have significant inhibitory effect on human erythroleukemia K562 cell. The pharmacological activities of other species in this genus were also frequently reported, and chemical constituents & pharmacological activities of this genus is worthy of in-depth research. In order to reveal the research progress of active components and bioactive ingredients such as flavonoids, volatile oil and terpenoids in Chrysosplenium spp, the major chemical constituents and pharmacological activities of Chrysosplenium were discussed in this paper.
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