汪文俊,王胜军,余诚,余程,向福.葡甘露聚糖-虾青素复合物的表征及对AFB1致肉鸡肝损伤的影响[J].中南民族大学学报自然科学版,2019,(2):184-188
葡甘露聚糖-虾青素复合物的表征及对AFB1致肉鸡肝损伤的影响
Characterization of glucomannan-astaxanthin complex and its effect on broiler liver injury induced by AFB1
  
DOI:10.12130/znmdzk.20190206
中文关键词: 葡甘露聚糖  虾青素  红法夫酵母  肝损伤  黄曲霉毒素B1  肉鸡
英文关键词: glucomannan  astaxanthin  Phaffia rhodozyma  liver injury  aflatoxin B1  broiler
基金项目:湖北省自然科学基金资助项目(2016CFB487);中央高校基本科研业务费专项资金重点资助项目(CZZ16003)
作者单位
汪文俊1,王胜军1,余诚2,余程1,向福3* 1 武陵山区特色资源植物种质保护与利用湖北省重点实验室中南民族大学 生命科学学院武汉4300742 湖北省武昌实验中学高二(9)班武汉 430060 3 大别山特色资源开发湖北省协同创新中心黄冈师范学院黄冈 438000 
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中文摘要:
      从红法夫酵母提取了葡甘露聚糖、虾青素并制备了葡甘露聚糖-虾青素(GM-ASTA)复合物,对其进行了红外光谱、热失重(TGA)分析和分子对接模拟分析,探讨了GM-ASTA复合物对黄曲霉毒素B1(AFB1)致肉仔鸡肝损伤的影响.结果表明:葡甘露聚糖和虾青素形成了复合物,前者主链通过范德华力和静电力与后者紧密结合. GM-ASTA复合物能显著地改善AFB1导致的肉鸡肝损伤后果,具有吸附并解除AFB1毒性的双重功效.
英文摘要:
      Glucomannan(GM) and astaxanthin(ASTA) were extracted from Phaffia rhodozyma and their GM-ASTA complex were prepared and investigated by infrared (IR) spectroscopy, thermogravimetric analysis (TGA) and molecular docking simulation analysis. The effects of ASTA complex on aflatoxin B1 (AFB1)-induced liver injury in broilers were also discussed. The results indicated that a complex was formed by GM and ASTA,which was combined by van der Waals and electrostatic forces between the GM main chain and ASTA.GM-ASTA complex could significantly improve the liver injury induced by AFB1 in broilers and had the dual effects of absorbing and removing AFB1.
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