刘新桥,韩海燕,覃彬华,王静.肺形草的化学成分研究[J].中南民族大学学报自然科学版,2019,(2):215-218
肺形草的化学成分研究
Research on the chemical constituents of Tripterospermum chinense
  
DOI:10.12130/znmdzk.20190212
中文关键词: 龙胆科  肺形草  化学成分
英文关键词: Gentianaceae  Tripterospermum chinense (Migo) H. Smith  chemical constituents
基金项目:国家科技支撑计划资助项目(2012BAI27B07);中央高校基本科研业务费专项资金资助项目(CZQ17021)
作者单位
刘新桥,韩海燕,覃彬华,王静 中南民族大学 药学院武汉 430074 
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中文摘要:
      为研究肺形草的化学成分,采用硅胶柱色谱、葡聚糖凝胶Sephadex LH-20、反相高效液相制备色谱对该植物的乙酸乙酯层进行分离纯化,通过1H NMR和13C NMR波谱技术进行结构鉴定.结果表明:从乙酸乙酯层中分离得到了8个化合物,分别鉴定为2'-acetamido-3'-phenylpropyl 2-benzamido-3-phenyl propionate(1)、1, 3, 5三羟基口山酮(2)、3-羟基-4-甲氧基苯甲酸甲酯(3)、咖啡酸乙酯(4)、邻苯二甲酸二丁酯(5)、1, 7-二羟基-3, 8-二甲氧基口山酮(6)、morroniside(7)、1, 3, 7-三羟基-4-C-β-D-葡萄糖基呫吨酮(8).其中化合物1~5为首次从该植物中分离得到.
英文摘要:
      To investigate the chemical constituents of Tripterospermum chinense, the EtOAc extract of the whole plant were separated and purified by column chromatography with silica gel, Sephadex LH-20 and ODS-HPLC. The structures of the constituents were identified by 1H NMR and 13C NMR. The results indicated that eight compounds were isolated from the extract and identified as 2'-acetamido-3'-phenylpropyl 2-benzamido-3-phenyl propionate(1), 1,3,5-trihydroxyxanthone(2), 3-Hydroxy-4-methoxy-benzoic acid methyl ester(3), ethyl caffeate(4), dibutyl phthalate(5), 1,7-dihydroxy-3, 8-dimethoxyxanthone(6), morroniside (7), lancerin(8). The compounds 1?5 were isolated from this plant for the first time.
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